Symposium

Symposia 1 Hypothalamic regulation of body energy homeostasis

This session covers three topics related to the functions of the brain's hypothalamus, a crucial brain region regulating various body homeostasis. Throughout the session, attendees will gain insights into the intricate mechanisms and regulatory pathways that govern various aspects of hypothalamic function. From genetic regulation impacting hypothalamic neurodevelopment and its link to obesity, to novel mechanisms underlying orexin-induced feeding behavior, and the intriguing role of hypothalamic neural stem cells in the aging process, each topic promises to offer profound understandings into the complexities of hypothalamic function and its implications for overall health and well-being.

Date & Time
October 31st(Thursday), 9:30 ~ 11:00, Room A 유광사홀
Organizer and Chair
Ki Woo Kim (Yonsei Univ.),
Co-Chair
Sung Hyun Kim (Kyung Hee Univ.)
Name Affiliation Title
1 Joe Eun Son Kyungpook National Univ. Genetic Regulation of Hypothalamic Neurodevelopment and Obesity
2 Jong-Woo Sohn KAIST Novel hypothalamic mechanisms for orexin-induced feeding
3 Min Soo Kim KIST Hypothalamic neural stem cell in aging.

Symposia 2 Progress, Challenges and Prospects in Gene Editing

With the remarkable advancements in gene-editing technology, it is now possible to edit genetic sequences in most eukaryotic cells. This technology has expanded the scope of physiological research into human diseases by enabling the development of more precise cellular and animal models. Additionally, it could contribute to the development of new therapeutic tools for human diseases. Recently, "exa-cel," the world's first gene-editing therapy, was approved, marking a significant milestone. This session will cover the fundamental principles and applications of CRISPR-based gene editing, with a discussion on its future potential.

Date & Time
October 31st(Thursday), 9:30 ~ 11:00, Room B 320호 최덕경
Organizer and Chair
Kyoungmi Kim (Korea Univ.)
Co-Chair
Hyunji Lee (Korea Univ.)
Name Affiliation Title
1 Kyoungmi Kim Korea Univ. A novel approach using CRISPR-ribonucleoprotein packaged in virus-like particles to generate genetically engineered mouse models
2 Hyunji Lee Korea Univ. Mitochondrial genome editing
3 Hunsang Lee Korea Univ. A functional genomics approach to map extracellular interactions
4 Won Do Heo KAIST Controlling and Visualizing Molecualr and Cellular Behavior in Living Cells and Animals

Symposia 3 Innovative new drug development : Basic infrastructural technologies for successful drug development and application of latest technologies in drug screening provided by K-MEDI hub

This session aims to provide a detailed explanation of the latest technologies supported by the Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI hub) for the development of innovative drugs. It will focus on two key areas: (1) target validation and efficacy evaluation, and (2) the supporting technologies from K-MEDI hub to the researcher in the field of drug development.

Date & Time
October 31st(Thursday), 9:30 ~ 11:00, Room C 418호 윤주홍
Organizer and Chair
Se Jin Jung (K-MEDI hub)
Co-Chair
Hyung Gee Kim (Korea Univ.)
Name Affiliation Title
1 Hyewon Seo K-MEDI hub Small Molecules, Big Discoveries: Accelerating Drug Development with DNA-encoded library Screening
2 Bae Jun Oh K-MEDI hub Development of human pluripotent stem cell-derived organoids for preclinical studies
3 Jung, Hoesu K-MEDI hub Introduction of research and efficacy evaluation technique using in-vivo bioimaging
4 Lee, Mi-Kyung KRIBB Development of single-molecule based next-generation drug screening technology

Symposia 4 Channels in Action: Advances in Mechanosensitive Ion Channel Research & Clinical Implications

This session centers on one of the most fascinating areas in life sciences: Mechanosensitive Ion Channels. These channels provide a fundamental means for cells to detect and respond to physical forces. We will explore the latest research and discoveries about the structure, function, and biological significance of these ion channels. This session is a tribute to the pioneering work of a notable scientist who paved the way for several researchers in our country to conduct ion channel research.

Date & Time
October 31st(Thursday), 14:00 ~ 15:30, Room A 유광사홀
Organizer and Chair
Dawon Kang (Gyeongsang National Univ.)
Donghee Kim ( Rosalind Franklin Univ.)
Name Affiliation Title
1 Uhtaek Oh KIST Structural prediction of Tentonin 3, a mechanosensitive channel
2 Sung Joon Kim Seoul National Univ. Tracking back TREK-2 K+ channels; PIP2, mechanosensitivity and the C-terminal charged residues
3 Young Min Bae Konkuk Univ. Signal transduction of Merkel cells in response to mechanical stimuli
4 Dawon Kang Gyeongsang National Univ. Mechanosensitive TREK Channels: Exploring Their Role in Neuroinflammation and Alzheimer’s Disease Progression

Symposia 5 Cutting-edge academic session by the Korean J Physiol Pharmacol

To enhance the development and impact of the Korean Journal of Physiology and Pharmacology, we have organized this cutting-edge session composed of the lectures by the Best Article Awardees of the year, and lecture of newly joined editorial board member in the field of structural biology. Furthermore, we will have a seminar on the technical and ethical guides for the application of artificial intelligence in academic writing.

Date & Time
October 31st(Thursday), 14:00 ~ 15:30, Room B 320호 최덕경
Organizer and Chair
Sun Hee Woo (Chungnam National Univ.)
Co-Chair
Cha, Seung-Kuy (Yonsei University Wonju),
Park, Sang-Min (Chungnam National Univ.)
Name Affiliation Title
1 Sang Jeong Kim Seoul National Univ. Altered inhibitory circuit of the medial prefrontal cortexin a mouse model of neuropathic pain
2 Sang-Pil Yoon JeiJu National Univ. Overcoming chemo-resistance of cancer via drug repurposing or natural medicine
3 Ka Young Chung Sung Kyun Kwan Univ. The alpha-helical domain of Gα, a new regulator of the heterotrimeric G protein signaling
4 Sangzin Ahn Inje Univ. Academic writing in the generative AI era

Symposia 6 Brain and cognitive aging

This session will present recent findings on functional changes in cognition related to aging and neurodegenerative diseases to promote attention in this research fields.

Date & Time
October 31st(Thursday), 14:00 ~ 15:30, Room C 418호 윤주홍
Organizer and Chair
Joong-Jean Park (Korea Univ.)
Name Affiliation Title
1 Joong-Jean Park Korea Univ. The Role of neurons and glial cells in controlling age-related memory impairment
2 Sung Bae Lee DGIST Unraveling pathomechanisms underlying ALS: a multiomics-based approach empowered by Drosophila genetics
3 Jinsoo Seo DGIST Protective influence of the APOE Christchurch Variant (R136S) against Alzheimer’s disease pathology linked to APOE4
4 Jee Hoon Roh Korea Univ. Increased risk of Alzheimer's disease affected by weight changes but not by body mass index

Symposia 7 Neural mechanism underlying learning and memory

The ability to take proper action depending on the knowledge learned from the external world is crucial in everyday life. The brain differentially recruits its circuitry in a given situation for an optimal outcome. In this symposium, we will discuss how different circuit modalities act on diverse learning and memory rules.

Date & Time
October 31st(Thursday), 16:00 ~ 17:30, Room A 유광사홀
Organizer and Chair
Alan Jung Park (Seoul National Univ.)
Name Affiliation Title
1 Jangjin Kim Kyungpook National Univ. Dynamic Neural Changes during Associative Learning
2 Yong-Seok Lee Seoul National Univ. Circuit mechanism underlying social memory in mice
3 Jung Ho Hyun DGIST Cellular learning rules for structural knowledge-based decision flexibility
4 Ja Wook Koo KBRI Role of mesocorticolimbic circuitry in social decision making
5 Seung-Hee Lee KAIST Flexibility and stability: multifaceted role of the posterior parietal cortex in reversal learning

Symposia 8 The Present and Future of Digestive Pathophysiology in Korean Medicine

In Korean medicine, the digestive tract is considered the central organ in all treatments. According to the theory of Spleen and Stomach (脾胃論), a deficiency of function of the spleen and stomach (脾胃虛) is regarded as the root cause of many diseases. Therefore, this session will provide an opportunity to reflect on the current and future challenges related to digestive tract dysfunction in Korean medicine.

Date & Time
October 31st(Thursday), 16:00 ~ 17:30, Room B 320호 최덕경
Organizer and Chair
Byung Joo Kim ( Pusan National Univ.)
Chair
Chang-Gue Son (Dae Jeon Univ.)
Name Affiliation Title
1 Young Woo Kim Dongguk Univ. Herbal drug candidate for the antioxidant properties and their metabolism
2 Byung Joo Kim Pusan National Univ. Atractylodes macrocephala Koidz Alleviates Symptoms in Zymosan-Induced Irritable Bowel Syndrome Mouse Model through TRPV1, NaV1.5, and NaV1.7 Channel Modulation
3 Chang-Eop Kim Gachon Univ. Identifying novel subtypes of functional gastrointestinal disorder by analyzing nonlinear structure in integrative biopsychosocial questionnaire data
4 Chang-Gue Son Dae Jeon Univ. Pathophysiology of Stress-Induced Liver Injury and Its Underlying Role

Symposia 9 Joint Symposium with Korean Society of Pharmacology

This session, jointly organized with the Korean Society of Pharmacology, aims to share the latest insights in pharmacology and physiology, fostering active discussions to identify potential convergence research topics for collaborative research.

Date & Time
October 31st(Thursday), 16:00 ~ 17:30, Room C 418호 윤주홍
Organizer and Chair
Jae-sung Bae (Kyungpook National Univ.)
Chair
Chi Dae Kim (Pusan National Univ.)
Sung Jun Kim (Seoul National Univ.)
Name Affiliation Title
1 Eun Kyung Lee Catholic Univ. Dynamic regulation of mitochondria in cellular senescence
2 Sung Kweon Cho Ajou Univ. Finding the Equilibrium for the Uric acid Dynamics
3 So-Young Park Yeungnam Univ. Senotherapeutic intervention as a treatment of metabolic diseases
4 Kyu Sang Park Wonju Yonsei Univ. Therapeutic strategies against age-related fibrotic diseases

Special Session Special Session with NRF :
National strategic R&D program about K-Brain project and Biomedical Engineering

Date & Time
October 31st(Thursday), 17:40 ~ 18:00, Room A 유광사홀
Chair
Jae-sung Bae (Kyungpook National Univ.)
Name Affiliation Title
1 Sung Hyun Kim Program Manager:
Division of Neuroscience and Advanced Medical Technology
National strategic R&D program about K-Brain project and Biomedical Engineering

Symposia 10 Exploring Glial Functions in CNS: Understanding Neuron-Glia Interactions

Glial cells, constituting approximately 90% of the cells in the Central Nervous System (CNS), are recognized as non-neuronal elements vital to CNS functionality. These cells are increasingly acknowledged as key mediators not only in normal brain function but also in neurodevelopmental, neurological, and neurodegenerative disorders. Despite various proposed mechanisms to elucidate the role of glial cells in both normal and pathological brain states, the exploration of these mechanisms at a physiological level is just beginning. This symposium aims to discuss recent studies focusing on the role of glial cells within neuron-glia interactions. We will delve into the complex interplay between neurons and glial cells in the context of both healthy and diseased brains. The symposium will examine the emerging roles of glial cells in CNS disorders, highlighting their potential in identifying therapeutic approaches. Additionally, we will propose new research directions in understanding the diverse functions of glial cells in the CNS, advancing our knowledge in this critical field of neuroscience.

Date & Time
November 1st(Friday), 9:00 ~ 10:30, Room A 유광사홀
Organizer and Chair
Hee Jung Kim (Dankook Univ.)
Chair
Dong Woon Kim (Kyung Hee Univ.)
Name Affiliation Title
1 Dong Woon Kim Kyung Hee Univ. Rejuvenating aged microglia increases amyloid-β clearance
2 Bo-Eun Yoon Dankook Univ. Bidirectional alteration of tonic inhibition from the core brain regions for motor and memory in a mouse model of ADHD
3 Soo-Jin Oh KIST The role of Tweety-homolog (TTYH) family in astrocyte volume regulation
4 Kyung-Ok Cho The Catholic Univ. of Korea Tracking oligodendroglial development through advanced imaging techniques

Symposia 11 Tissue-Specific Immunity: Exploring the Physiological Landscapes Across Different Organs

This session will explore the unique physiological landscapes of peripheral organs, focusing on the complex orchestration and regulation of immune responses within diverse tissue environments. We will examine the pivotal roles of tissue-resident immune cells, the specificity of localized immune signaling pathways, and the intricate dynamics of the tissue microenvironment that together shape immune function and influence pathological outcomes.

Date & Time
November 1st(Friday), 9:00 ~ 10:30, Room B 320호 최덕경
Organizer and Chair
June-Yong Lee (Yonsei Univ.)
Chair
You Jeong Lee (Seoul National Univ.)
Name Affiliation Title
1 You Jeong Lee Seoul National Univ. Human MAIT cells undergo clonal selection and expansion in the thymus with occasional expression of polyclonal dual TCRs
2 Jinwook Choi GIST Inflammatory Niche in Lung tissue regeneration and pathogenesis
3 Yong-Hyun Han Kangwon National Univ. Portal Immune System: Key Guardians against Gut-derived Toxins

Symposia 12 Novel therapeutic strategies for cardiovascular diseases – stem cell, miRNA, mitochondria and beyond

Cardiovascular diseases are leading causes of mortality and morbidity worldwide. Stem cell, miRNA therapies have been very much the focus of therapeutic targets. Recently, mitochondrial transplantation is emerged as a new strategy for ischemic related diseases including heart and vessel. Therefore, the current session will discuss current trend of treatment paradigm for cardiovascular diseases.

Date & Time
November 1st(Friday), 9:00 ~ 10:30, Room C 418호 윤주홍
Organizer and Chair
Yin Hua Zhang (Seoul National Univ.)
Name Affiliation Title
1 Hun Jun Park Catholic Univ. Stem cell bioengineering for cardiac repair
2 Hong Sun Xu Zhou Medical Univ Estrogen Mitigates Stress-Induced Cardiac Injury
3 Yin Hua Zhang Seoul National Univ Mitochondrial transplantation for ischemic related cardiovascular diseases

Symposia 13 Young Faculty Presentation Part 1. Neuroscience

This session features dynamic and inspiring presentations from professors who have been appointed within the last two years, bringing a fresh and dynamic perspective to their research. The speakers are selected to highlight cutting-edge research techniques that are currently trending, offering in-depth insights into their recent findings. The Young Faculty Presentation symposium is divided into three parts, with this segment focusing on Neuroscience. We look forward to exploring the advanced methodologies and high-level research outcomes that will be presented.

Date & Time
November 1st(Friday), 14:00 ~ 15:30, Room A 유광사홀
Organizer and Chair
Jun Young Heo (Chung Nam National Univ.)
Chair
Sang Jeong Kim (Seoul National Univ.)
Name Affiliation Title
1 Hyunsu Lee Pusan National Univ. AI in Neurobiology: From Neuron Classification to Reinforcement Learning Models
2 Alan Jung Park Seoul National Univ Identifying a biomarker for cognitive performance
3 Hongik Hwang Univ. of Seoul Functional significance of NRGN, a schizophrenia risk gene, in regulating synaptic plasticity and calcium channel activity
4 Bo Am Seo Yonsei Univ. Wonju Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease

Symposia 14 Young Faculty Presentation Part 2. Cancer and Metabolism

This session features dynamic and inspiring presentations from professors who have been appointed within the last two years, bringing a fresh and dynamic perspective to their research. The speakers are selected to highlight cutting-edge research techniques that are currently trending, offering in-depth insights into their recent findings. The Young Faculty Presentation symposium is divided into three parts, with this segment focusing on Cancer and Metabolism. We look forward to exploring the advanced methodologies and high-level research outcomes that will be presented.

Date & Time
November 1st(Friday), 14:00 ~ 15:30, Room B 320호 최덕경
Organizer and Chair
Jun Young Heo (Chung Nam National Univ.)
Chair
Hyoung Kyu Kim (Inje Univ.)
Name Affiliation Title
1 Jung-Hyun Kim National Cancer Center Unveiling the Role of SON-Mediated RNA Splicing in Genetic Diseases and Tumorigenesis
2 Joonbeom Bae Korea Univ. Tumor-targeted therapy using engineered mesenchymal stem cells remodels tumor microenvironment
3 Kwang-eun Kim Yonsei Univ. Wonju. In vivo mapping of subcellular proteomes in mice
4 Jin-Ho Koh Yonsei Univ. Wonju Exercise-induced-lactate promotes fatty acid oxidation by the TCA cycle and mitochondrial respiration in muscles of obese mice

Symposia 15 Young Faculty Presentation Part 3. Infection and Immunology

This session features dynamic and inspiring presentations from professors who have been appointed within the last two years, bringing a fresh and dynamic perspective to their research. The speakers are selected to highlight cutting-edge research techniques that are currently trending, offering in-depth insights into their recent findings. The Young Faculty Presentation symposium is divided into three parts, with this segment focusing on Infection and Immunology. We look forward to exploring the advanced methodologies and high-level research outcomes that will be presented.

Date & Time
November 1st(Friday), 14:00 ~ 15:30, Room C 418호 윤주홍
Organizer and Chair
Jun Young Heo (Chung Nam National Univ.)
Chair
Jihee Lee (Ewha Womans Univ.)
Name Affiliation Title
1 Hyunsu Lee Daegu Catholic Univ. Sesamin enhances apoptosis of activated T cells by physically interacting with MCL-1 and shows therapeutic effect on allergic dermatitis
2 Kyung Ku Jang Yeonsei Univ. Tofacitinib Uptake by patient-derived intestinal organoids predicts individual clinical responsiveness
3 Jinsung Yang Gyeongsang National Univ. Principles and applications of atomic force microscopy in studying virus entry mechanism
4 Dong-Yeon Kim Gyeongsang National Univ. In vivo imaging of invasive aspergillosis with 18F-fluorodeoxysorbitol positron emission tomography in small animals

Symposia 16 Inflammation and aging

One of the key physiological changes observed during the aging process is "inflamm-aging," which is increasingly recognized as a major contributor to the development of degenerative and chronic age-related diseases and has attracted considerable attention as an important therapeutic target. In this session, we will invite four distinguished speakers who are actively conducting research on inflammation and aging across various disease models to introduce the latest research trends in this field.

Date & Time
November 1st(Friday), 15:40 ~ 17:10, Room A 유광사홀
Organizer and Chair
Youn-Hee Choi ( Ewha Womans Univ.)
Name Affiliation Title
1 Jihee Lee Ewha Womans Univ. Role of interaction between cancer-associated fibroblasts and apoptotic cancer cells in lung cancer suppression
2 Tae Jun Park Ajou Univ. Novel target for antiaging intervention in the elderly: from the aspect of mid old cells
3 Ja-Hyoung Ryu UNIST Supramolecular senolytics via intracellular oligomerization of peptides
4 Min-Soo Kwon CHA univ. Senescent microglia: a universal target in brain aging and neurodegenerative diseases

Symposia 17 Exploring novel pain circuits from the periphery to the brain

Chronic pain remains a persistent and unresolved challenge. As a key strategy to address this issue, the development of novel non-opioid analgesics based on new pain-related neural circuits in the brain has emerged. This session will introduce the recent research focused on the identification of new pain circuits, from the periphery to the brain, as well as the elucidation of their cellular and molecular mechanisms.

Date & Time
November 1st(Friday), 15:40 ~ 17:10, Room B 320호 최덕경
Organizer and Chair
Sun Kwang Kim ( Kyung Hee Univ.)
Name Affiliation Title
1 Euiheon Chung GIST Translational neurophotonics for visualizing and manipulating the nervous system
2 Seog Bae OH Seoul National Univ. Neuroimmunity in Pain: Role of Natural Killer Cells
3 Sang Jeong Kim Seoul National Univ. Nocifensive behavior-associated activation of cerebellar Bergmann glia modulate chronic neuropathic pain
4 Geehoon Chung Neurogrin Company Metabotropic glutamate receptors in the brain show characteristic patterns in neuropathic pain state

Symposia 18 Revealing underlying mechanism of metabophyiology through Multi-omics analysis

The aim of this session is to present a new paradigm in the regulation of metabolic control mechanisms through multi-omics analysis in chronic metabolic diseases such as NAFLD, cancer, and diabetes, and to enhance our understanding of metabolic physiological processes.

Date & Time
November 1st(Friday), 15:40 ~ 17:10, Room C 418호 윤주홍
Organizer and Chair
Seung-Soon Im ( Keimyung Univ.)
KyeongJin Kim (Inha Unviv.)
Name Affiliation Title
1 Wondong Kim Hanyang Univ. The Role of NAD+ Recycling at the Nexus of Glucose and Lipid Metabolism
2 Yoon Mee Yang Kangwon National Univ. Fibrotic Tumor Microenvironment Promotes Metastatic Tumor Growth in Fatty Liver
3 Min-Sik Lee POSTECH Nearby nutrients dictate metabolism and maintain open chromatin landscape to support cancer growth
4 Yong-Uk Lee Dankook Univ. Host and microbial compensation in a model of leucine breakdown deficienty

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